Welcome to the Adolescent Medicine Trials Network for HIV Interventions (ATN)
Youth-Centered Research
Community-Driven Change
Youth-Centered Research | Community-Driven Change
What is the ATN?
The Adolescent Medicine Trials Network for HIV Interventions (ATN) conducts innovative and collaborative research that explores promising strategies to support sexual health among adolescents and young adults ages 13 through 24.
The ATN is the only research network in the United States devoted solely to HIV prevention and care for youth, bringing together adolescents, communities, and researchers to enrich the health and well-being of youth and young adults.
Get Involved
You can help make HIV prevention and care options more accessible for youth by participating in our research.
Learn more about each of our active studies and find out if you qualify!
Are you a researcher, academic, or policymaker looking to dive deeper into the data or explore events for a scientific audience? Visit the ATN Connect website.
By the Numbers
Community Toolbox
The ATN is committed to sharing our research back to the community.
We tailor our research findings to meet the needs of different audiences through a range of materials, such as infographics for youth, toolkits and resources for community organizations, and peer-reviewed journal publications for researchers.
Featured News
The LYPS & CHOOSE Studies are Open for Enrollment
This August, the Linking Youth to PrEP Services (LYPS) study and Combatting HIV or Other STIs Early (CHOOSE) study opened for enrollment!
The LYPS study is exploring community-based PrEP services to better support young people taking PrEP over time. It’s currently enrolling in Houston and San Francisco, and will open in Atlanta and Baltimore soon.
The CHOOSE study is testing whether tailored digital tools with information about PrEP and DoxyPEP help young men choose the best type of PrEP for them and take the medications as recommended. It’s currently enrolling in Washington, D.C. and will open in Chicago, Memphis, New Orleans, San Francisco, and Tampa soon.
Published Aug. 2026
ATN Launches the Screen2Prevent Study
How can we make HIV testing easier and more accessible for young people—especially in places they already go for care? The Screen2Prevent (S2P) study is exploring HIV screening for youth who are seen in emergency departments.
By testing three different approaches—universal, opt-out, and focused screening—the S2P study aims to find what works best to reach more young people. The study also uses a quick digital survey to identify who may benefit from PrEP, plus a texting tool to help connect them to prevention services.
Participation in this study is limited to people who receive care at specific emergency departments.
Published June 2026
The foXXy doxy Study is Open for Enrollment!
The foXXy doxy study opened for enrollment in early 2026!
Doxycycline is an FDA-approved antibiotic that is widely used to prevent and treat certain sexually transmitted infections (STIs) like gonorrhea, chlamydia, and syphilis. Taking doxycycline after condomless sex (on-demand) or weekly, a strategy called “DoxyPEP,” is approved for use among some populations, like men.
The foXXy doxy study aims to close a gap in data by determining whether DoxyPEP is effective for women, too.
Published Jan. 2026
Stay In-the-Know!
Receive email alerts about research findings or opportunities to participate in new studies.
We also share findings and research opportunities on social media. Follow @ATNresearch!
