We can’t do this crucial research without YOUth.
The ATN is seeking young people to join us in advancing public health! We’re enrolling volunteers into paid research studies.
A healthier future starts with you—take the next step to find out if you qualify.
The IMPACT Study
For young people ages 16-24 who have had condomless sex while using stimulants
Combining evidence-based talk therapy to treat depression and sexual health counseling for young people who use stimulants to (1) encourage youth to reengage in healthier activities they enjoy and (2) reduce the likelihood of getting or transmitting HIV.
Get up to $825 for completing harm reduction talk therapy and sexual health counseling sessions.
The foXXy doxy Study
For females ages 13-29 who have had an STI (gonorrhea, chlamydia, or syphilis) in the past 12 months
Testing if DoxyPEP, an antibiotic already proven to prevent certain STIs among men, can prevent STIs for more young people.
In Analysis
These studies have completed enrollment and are in the analysis phase. When we have findings available, we will share them directly with former participants and broadly across our social media channels.
HIV and Pregnancy Protection for Youth (HAPPY)
Exploring values and preferences among young people ages 15-24 for features of a new long-acting medication that will prevent both HIV and pregnancy
What did the HAPPY study do?
What’s next?
Findings will inform ATN 172, which will develop and test the new medication.
Full Title: ATN 168: HIV and Pregnancy Prevention for Youth (HAPPY)
Upcoming Studies
These studies have not opened for enrollment yet.
Would you like to receive emails about new research opportunities and what we’ve learned from our studies?
The Linking Youth to PrEP Services (LYPS) Study
Aiming to improve PrEP use among young people by combining the use of a Community Health Provider to provide PrEP services at a location the participant chooses outside the clinic (e.g., in a private room in a community center) with a smartphone-based app to support PrEP use between services.
Opening January 2026!
Who may be eligible?
Young people ages 13-24 who may benefit from PrEP for HIV prevention
Where is the LYPS study study enrolling?
What would I do?
Get up to $400 to attend no-cost PrEP care visits every 2-3 months over the course of 9 months
Full Title: ATN 165: Linking Youth to PrEP Services (LYPS): An Innovative Mobile Delivery and Mobile Health Intervention to Optimize PrEP Adherence and Persistence
ClinicalTrials.gov Number | Pending
The Combating HIV or Other STIs Early (CHOOSE) Study
Testing whether tailored digital tools with information about PrEP and DoxyPEP help young men choose the best type of PrEP for them and take the medications as recommended.
Opening March 2026!
Who may be eligible?
Young men ages 13-24 who are not currently taking PrEP and interested in learning more about it
Where is the CHOOSE study enrolling?
What would I do?
Get up to $800 to receive PrEP and DoxyPEP counseling and medication at no cost, attend quarterly study visits, and complete surveys across 18 months
Full Title: ATN 166: Combatting HIV or Other STIs Early (CHOOSE)
ClinicalTrials.gov Number | Pending
The Screen2Prevent Study
Finding the best way to increase HIV screening rates among youth in pediatric emergency departments and using a texting tool to connect youth to PrEP care.
Opening June 2026!
Who may be eligible?
Young people ages 14-24 receiving care in select pediatric emergency departments
Where is the Screen2Prevent study enrolling?
Full Title: ATN 164: Using Digital Health to Improve HIV Screening and Prevention for Adolescents in the Emergency Department (Screen2Prevent)
ClinicalTrials.gov Number | Pending
The HIV and Pregnancy Protection for Youth (HAPPY) Study, Part 2
Developing a new, long-acting medication that prevents both pregnancy and HIV.
When will enrollment begin?
Slated to open for enrollment in 2026
Who May Be Eligible?
Young women ages 18-24 who are not living with HIV
Full Title: ATN 172: HIV and Pregnancy Prevention for Youth (HAPPY)
Open Studies
Dive into each of our studies that are currently enrolling participants to learn more about what’s involved and who may be eligible.
The foXXy doxy Study
Testing if DoxyPEP, an antibiotic already proven to prevent certain STIs among men, can prevent STIs for more young people.
Who may be eligible?
Women ages 13-29 who have had an STI (gonorrhea, chlamydia, or syphilis) in the past 12 months
Where is the foXXy doxy study enrolling?
What would I do?
Get up to $400 for taking DoxyPEP as prescribed and completing 7 study visits, some of which include STI testing
Full Title: ATN 173: Doxycycline Prophylaxis for Prevention of STIs Among Adolescent and Adult Females (foXXy doxy)
ClinicalTrials.gov Number |NCT06738407
The IMPACT Study
Combining evidence-based talk therapy to treat depression and sexual health counseling for young people who use stimulants to:
(1) encourage youth to reengage in healthier activities they enjoy and
(2) reduce the likelihood of getting or transmitting HIV
Who may be eligible?
Young people ages 16-24 who have had condomless sex while using stimulants
Where is the IMPACT study enrolling?
Nationwide, excluding Alaska and Hawai‘i
What would I do?
Get up to $825 to complete surveys and participate in talk therapy and sexual health counseling sessions over the course of 12 months
Full Title: ATN 170: Behavioral Activation and Risk Reduction for Stimulant Use Among Sexually Active Adolescents and Young Adults (IMPACT)
ClinicalTrials.gov Number |NCT06444360